Gene interactions and pathways from curated databases and text-mining

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RNF19A — TNFSF11

Text-mined interactions from Literome

Rahman et al., J Lipid Res 2006 (Bone Resorption) : CLA also inhibited RANKL induced activation of mitogen activated protein kinase p38 but had little effect on c-Jun N-terminal kinase activation
Chen et al., Assay Drug Dev Technol 2006 : Compound 1 did not inhibit the RANKL induced activation of a NF-kappaB reporter gene, or p38 kinase activity, suggesting a mechanism of action downstream of NF-kappaB
Rossa et al., J Interferon Cytokine Res 2006 (MAP Kinase Signaling System) : MKK3/6-p38 MAPK signaling is required for IL-1beta and TNF-alpha induced RANKL expression in bone marrow stromal cells
Rossa et al., J Periodontal Res 2008 (MAP Kinase Signaling System) : Inhibiting p38 MAPK prior to lipopolysaccharide stimulation resulted in a significant decrease of RANKL mRNA expression
Chen et al., J Biol Chem 2008 : Importantly, PLCgamma2 deficiency severely impaired RANKL signaling, resulting in marked reduction of RANKL induced activation of MAPKs, p38 and JNK, but not ERK