Gene interactions and pathways from curated databases and text-mining

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CXCL2 — ROCK1

Text-mined interactions from Literome

Struckhoff et al., J Cell Sci 2010 : Interestingly, CXCL12 partially reduces the level of ROCK activity generated by attachment, which supports a model in which stimulation with CXCL12 regulates tumor cell adhesion events by providing an optimal level of ROCK activity for effective migration
Rafferty et al., Cell Immunol 2012 : Suppressing ROCK with the Y27632 inhibitor suppressed IL-1 stimulated Caco-2 cell CXCL8/IL-8 and IEC-6 cell CCL2/MCP-1 secretion and mRNA levels