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SAA1 — TP63

Text-mined interactions from Literome

He et al., J Immunol 2006 : In peripheral blood monocytes and the THP-1 monocytic cell line, SAA induces the expression of IL-12p40 , a subunit shared by IL-12 and IL-23 ... SAA stimulated expression of IL-12p40 was rapid ( < or = 4 h ), sustainable ( > or = 20 h ), potent ( up to 3380 pg/ml/10 ( 6 ) cells in 24 h ), and insensitive to polymyxin B treatment ... The SAA stimulated IL-12p40 secretion required de novo protein synthesis and was accompanied by activation of the transcription factors NF-kappaB and C/EBP
Migita et al., Clin Exp Immunol 2010 (Arthritis, Rheumatoid) : Interestingly, the SAA induced IL-23, p19 and p40 production was accompanied by enhanced expression of IL-1ß, but not transforming growth factor-ß