Gene interactions and pathways from curated databases and text-mining

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ICAM1 — SELPLG

Text-mined interactions from Literome

Atarashi et al., J Immunol 2005 : In this study, we show that Ab-mediated cross linking of the PSGL-1 on Th1 cells enhances LFA-1 dependent cell binding to ICAM-1 ... PSGL-1 cross linking did not enhance soluble ICAM-1 binding but induced clustering of LFA-1 on the cell surface, suggesting that an increase in LFA-1 avidity may account for the enhanced binding to ICAM-1
Yao et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2008 : The expression of CD162 was downregulated and CD54 was first increased but then dropped to the level before co-culture
Yoshizaki et al., J Immunol 2010 (Fibrosis...) : This study suggests that L-selectin and ICAM-1 regulate Th2 and Th17 cell accumulation into the skin and lung, leading to the development of fibrosis, and that P-selectin, E-selectin, and PSGL-1 regulate Th1 cell infiltration, resulting in the inhibition of fibrosis