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MMP1 — SERPINE1

Text-mined interactions from Literome

Gillette et al., Tumori 2003 : We detected MMP-7, urokinase plasminogen activator (uPA) and PAI-1 in both Matrigels, TIMP-2 was detected only in regular Matrigel and no MMP-1 or TIMP-1 was detected in either matrix
Wu et al., Cancer Res 2006 (Helicobacter Infections...) : Maximal activation of MMP-1 transcription requires the cag PAI and OipA, which regulate AP-1 and PEA-3 binding
Ghosh et al., J Cell Physiol 2012 (Fibrosis) : Under normal physiologic conditions, PAI-1 controls the activities of uPA/tPA/plasmin/MMP proteolytic activities and thus maintains the tissue homeostasis ... During wound healing, elevated levels of PAI-1 inhibit uPA/tPA/plasmin and plasmin dependent MMP activities, and, thus, help expedite wound healing