Gene interactions and pathways from curated databases and text-mining

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CCL2 — SERPINF1

Text-mined interactions from Literome

Inagaki et al., Diabetologia 2003 : Pigment epithelium derived factor inhibits the AGE induced reactive oxygen species generation and the subsequent increase in MCP-1 production in microvascular endothelial cells
Wang et al., American journal of physiology. Renal physiology 2008 (Diabetes Mellitus, Experimental...) : In cultured primary human renal mesangial cells ( HMC ), the high-glucose medium induced upregulation of VEGF and MCP-1 was largely blocked by PEDF
Zhang et al., J Mol Endocrinol 2008 (Inflammation) : PEDF also attenuated the HOG-LDL induced NF-kappaB activation, suggesting that the inhibitory effect of PEDF on MCP-1 was at least partially through the blockade of NF-kappaB activation