Gene interactions and pathways from curated databases and text-mining

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FOXO1 — SETD2

Text-mined interactions from Literome

Alam et al., Endocrinology 2009 : These results indicate that FSH stimulated HIF-1 activation leading to up-regulation of targets such as vascular endothelial growth factor requires not only PI3-kinase/AKT mediated activation of mammalian target of rapamycin as well as phosphorylation of FOXO1 and possibly MDM2 but also a protein ( kinase ) activity that is inhibited by the classic ERK kinase inhibitor PD98059 but not ERK1/2 or 5
Kim et al., BMC cancer 2011 (Carcinoma...) : In addition, cell culture experiments showed that FOXO1 suppression increased the mRNA and protein expressions of HIF-1a