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SKP1 — STAT5A

Text-mined interactions from Literome

Boer et al., Exp Hematol 2003 : STAT5 activation was examined in erythroid cell lines by analyzing the effects of EPO and SCF on STAT5 tyrosine phosphorylation, serine phosphorylation, DNA binding, and STAT5 mediated gene transactivation ... SCF pretreatment followed by EPO stimulation resulted in a 9.0-fold+/-0.9-fold increase in STAT5 transactivation, while SCF alone did not increase STAT5 transactivation ... SCF enhances the EPO mediated STAT5 transactivation by triggering a PKA/CREB dependent pathway
Drayer et al., Stem Cells 2005 : TPO stimulation of MO7e cells resulted in STAT5 transactivation, which could be enhanced 1.6-fold by costimulation with SCF, whereas SCF alone did not induce STAT5 transcriptional activity
Pallard et al., EMBO J 1995 (Leukemia, Megakaryoblastic, Acute) : In contrast, neither interferon (IFN)-gamma nor the mitogenic stem cell factor (SCF) activated STAT5 , although IFN-gamma did activate STAT1 in those cells
Ryan et al., Exp Hematol 1997 : These data indicate that SCF stimulation of Kit leads to activation of STAT-5 DNA binding with kinetics distinct from Epo mediated stimulation