Cardone et al., Mol Biol Cell 2007
(Anoxia...) :
The NHERF1 PDZ2 domain regulates PKA-RhoA-p38 mediated NHE1 activation and invasion in breast tumor cells
Mandal et al., Am J Physiol Cell Physiol 2008
(Ion Channel Gating) :
Taken together, the results are consistent with increased capacitative calcium entry and subsequent cAMP-PKA dependent stimulation of NHE1 in ouabain treated cells
Cabral et al., J Pharmacol Exp Ther 2013
(Colonic Neoplasms) :
A significant increase in cAMP levels ( 32 ± 3 % and 14 ± 2 % after short- and long-term stimulation, respectively ) was detected, and inhibition of protein kinase A (PKA) , phospholipase C (PLC), and downregulation of protein kinase C ( PKC ) prevented NHE1 inhibition