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FOXP3 — SLIT2

Text-mined interactions from Literome

Nieminen et al., Pediatr Allergy Immunol 2010 (Rhinitis, Allergic, Seasonal) : This randomized, placebo controlled dose-response study was performed to analyze the effects of SLIT on FOXP3 , IL-17, IL-23, and IL-27 expressions in peripheral blood mononuclear cells ( PBMC ) of children with allergic rhinitis and their associations with clinical outcome
Swamy et al., J Allergy Clin Immunol 2012 (Rhinitis, Allergic, Seasonal) : Dual SLIT promoted allergen-specific suppressive CD4 ( + ) CD25 ( high ) CD127 ( low ) CD45RO ( + ) forkhead box protein 3 (Foxp3) ( + ) memory regulatory T cells with reduced DNA methylation of CpG sites within the Foxp3 locus ... The results of this pilot study suggest that dual SLIT could be an effective means to treat subjects with sensitivities to a variety of allergens and that long-term tolerance might be induced by epigenetic modifications of Foxp3 in memory regulatory T cells