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S100A8 — SMAD3
Text-mined interactions from Literome
Dooley et al., Gastroenterology 2003
(Liver Cirrhosis) :
Smad7 expression totally blocked TGF-beta signal transduction, shown by inhibiting Smad2/3 phosphorylation, nuclear translocation of activated
Smad complexes, and
activation of (
CAGA ) ( 9 ) -MLP-Luc, resulting in decreased collagen I expression ... Smad7 expression totally blocked TGF-beta signal transduction, shown by inhibiting
Smad2/3 phosphorylation, nuclear translocation of activated Smad complexes, and
activation of (
CAGA ) ( 9 ) -MLP-Luc, resulting in decreased collagen I expression
Spicer et al., J Endocrinol 2006
:
Treatment with GDF-9 ( but not BMP-4 ) activated the
Smad3 induced
CAGA promoter activity, whereas BMP-4 ( but not GDF-9 ) activated the Smad1/5/8 induced BRE promoter activity