Gene interactions and pathways from curated databases and text-mining

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CASP12 — SMARCC1

Text-mined interactions from Literome

Delaney et al., J Neuropathol Exp Neurol 2001 (Diabetic Neuropathies) : High glucose induces caspase cleavage in apoptotic SCs -- an effect that is blocked by bok-asp-fmk (BAF) , a caspase inhibitor
Zaidi et al., J Neuropathol Exp Neurol 2001 : Cell death was inhibited by 3-methyladenine, an inhibitor of autophagic vacuole formation, but not by Boc-Asp-FMK (BAF) , a broad caspase inhibitor
Bhat et al., J Alzheimers Dis 2002 : To determine whether these pathways interact from a signalling perspective, we compared the effects of BAF ( a general caspase inhibitor ), Li+ ( a GSK3beta inhibitor ) and insulin on NGF-W induced PC12 cell death ... BAF inhibited caspase-3 activity and delayed cell death up to 6 h after NGF-W indicating that caspase inhibition is sufficient to prevent apoptosis
Furukawa et al., J Struct Biol 2007 : This BAF loss was not detected before drICE activation and was inhibited by Ac-DEVD-CHO caspase inhibitors