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FGF23 — SPRY2

Text-mined interactions from Literome

Impagnatiello et al., J Cell Biol 2001 (MAP Kinase Signaling System) : Overexpressed Spry-1 and -2 inhibit fibroblast growth factor- and vascular endothelial growth factor induced proliferation and differentiation by repressing pathways leading to p42/44 mitogen activating protein ( MAP ) kinase activation
Szabo-Rogers et al., Dev Biol 2008 : Instead it is more likely that the foil repressed FGF signaling perhaps mediated by the increase in SPRY2 expression
Sugiura et al., Biol Reprod 2009 : Oocytes suppressed basal and FGF stimulated Spry2 mRNA levels in cumulus cells but promoted EGF stimulated levels ... Therefore, oocyte derived members of the TGFbeta superfamily suppress FGF stimulated Spry2 mRNA levels before the luteinizing hormone surge but promote Spry2 mRNA levels stimulated by EGF receptor mediated signals after the surge
Edwin et al., J Biol Chem 2010 : Mnk2 silencing decreased Spry2-Nedd4 interactions and also augmented the ability of Spry2 to inhibit fibroblast growth factor signaling