Gene interactions and pathways from curated databases and text-mining

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ITGB1 — SPTAN1

Pathways - manually collected, often from reviews:

  • BioCarta ucalpain and friends in cell spread: FODRIN (SPTAN1) → Integrin-alpha/Integrin-beta/ECM complex (ITGA1-ITGB1) (modification, collaborate)
  • BioCarta ucalpain and friends in cell spread: FODRIN (SPTAN1) → Paxillin/FAK/Talin/SPTAN1/Integrin-alpha/Integrin-beta/ECM/SRC/Ezrin complex (PXN-PTK2-TLN1-SPTAN1-ITGA1-ITGB1-SRC-VIL2) (modification, collaborate)
  • BioCarta ucalpain and friends in cell spread: Calpain1 complex (CAPNS1-CAPN1) → Paxillin/FAK/Talin/SPTAN1/Integrin-alpha/Integrin-beta/ECM/SRC/Ezrin complex (PXN-PTK2-TLN1-SPTAN1-ITGA1-ITGB1-SRC-VIL2) (modification, activates)
  • BioCarta ucalpain and friends in cell spread: Integrin-alpha/Integrin-beta/ECM complex (ITGA1-ITGB1) → Paxillin/FAK/Talin/SPTAN1/Integrin-alpha/Integrin-beta/ECM/SRC/Ezrin complex (PXN-PTK2-TLN1-SPTAN1-ITGA1-ITGB1-SRC-VIL2) (modification, collaborate)
  • BioCarta ucalpain and friends in cell spread: RAC1 → Paxillin/alpha-actinin/Talin/SPTAN1/Integrin-alpha/Integrin-beta/ECM/SRC/Ezrin complex (PXN-ACTN3_ACTN2_ACTN1_ACTN4-TLN1-SPTAN1-ITGA1-ITGB1-VIL2) (modification, activates)
  • BioCarta ucalpain and friends in cell spread: Talin (TLN1) → Paxillin/alpha-actinin/Talin/SPTAN1/Integrin-alpha/Integrin-beta/ECM/SRC/Ezrin complex (PXN-ACTN3_ACTN2_ACTN1_ACTN4-TLN1-SPTAN1-ITGA1-ITGB1-VIL2) (modification, collaborate)
  • BioCarta ucalpain and friends in cell spread: Paxillin/alpha-actinin/Talin/SPTAN1/Integrin-alpha/Integrin-beta/ECM/SRC/Ezrin complex (PXN-ACTN3_ACTN2_ACTN1_ACTN4-TLN1-SPTAN1-ITGA1-ITGB1-VIL2) → Integrin-alpha/Integrin-beta/ECM complex (ITGA1-ITGB1) (modification, collaborate)
  • BioCarta ucalpain and friends in cell spread: Paxillin/alpha-actinin/Talin/SPTAN1/Integrin-alpha/Integrin-beta/ECM/SRC/Ezrin complex (PXN-ACTN3_ACTN2_ACTN1_ACTN4-TLN1-SPTAN1-ITGA1-ITGB1-VIL2) → FODRIN (SPTAN1) (modification, collaborate)
  • BioCarta ucalpain and friends in cell spread: Paxillin/alpha-actinin/Talin/SPTAN1/Integrin-alpha/Integrin-beta/ECM/SRC/Ezrin complex (PXN-ACTN3_ACTN2_ACTN1_ACTN4-TLN1-SPTAN1-ITGA1-ITGB1-VIL2) → Actin (ACTA1) (modification, collaborate)
  • BioCarta ucalpain and friends in cell spread: Paxillin/alpha-actinin/Talin/SPTAN1/Integrin-alpha/Integrin-beta/ECM/SRC/Ezrin complex (PXN-ACTN3_ACTN2_ACTN1_ACTN4-TLN1-SPTAN1-ITGA1-ITGB1-VIL2) → Ezrin (VIL2) (modification, collaborate)
  • BioCarta ucalpain and friends in cell spread: Paxillin/alpha-actinin/Talin/SPTAN1/Integrin-alpha/Integrin-beta/ECM/SRC/Ezrin complex (PXN-ACTN3_ACTN2_ACTN1_ACTN4-TLN1-SPTAN1-ITGA1-ITGB1-VIL2) → alpha-actinin (ACTN3/ACTN2/ACTN1/ACTN4) (modification, collaborate)
  • BioCarta ucalpain and friends in cell spread: Paxillin/alpha-actinin/Talin/SPTAN1/Integrin-alpha/Integrin-beta/ECM/SRC/Ezrin complex (PXN-ACTN3_ACTN2_ACTN1_ACTN4-TLN1-SPTAN1-ITGA1-ITGB1-VIL2) → PAX (PXN) (modification, collaborate)
  • BioCarta ucalpain and friends in cell spread: Integrin-alpha/Integrin-beta/ECM complex (ITGA1-ITGB1) → FODRIN (SPTAN1) (modification, collaborate)