Gene interactions and pathways from curated databases and text-mining

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GNB1 — SRC

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Piiper et al., Mol Pharmacol 2000 : Activation of extracellular regulated kinases 1 and 2 ( ERK1/2 ) by G protein coupled receptors has been described to occur either through a PTx-insensitive pathway involving activation of phospholipase C and protein kinase C ( PKC ), or through a PTx-sensitive pathway involving G(i)betagamma mediated activation of Src
Canet-Aviles et al., Brain Res Mol Brain Res 2002 (Alzheimer Disease...) : These data are discussed in relation to a pathway for the enhancement of sAPPalpha secretion by muscarine which involves the activation of a Src-TK by G-protein beta/gamma-subunits leading to activation of PKCalpha, and ERK1/2 by a mechanism not involving phospholipase C