Stephanou et al., J Biol Chem 2001
(Reperfusion Injury) :
Moreover, STAT-1 is critical for the induction of Fas receptor and Fas ligand expression by ischemia/reperfusion ( I/R ) ... These results indicate that Fas/FasL genes and apoptosis are activated by STAT-1 in cardiac myocytes exposed to I/R and these effects are dependent on the Ser-727 but not the Tyr-701 phosphorylation sites of STAT-1
Balasubramanian et al., J Infect Dis 2006
(Carcinoma, Hepatocellular...) :
STAT1 alpha overexpression increased cell apoptosis and Fas ligand expression, compared with STAT1 beta overexpression