Gene interactions and pathways from curated databases and text-mining

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CXCL2 — STAT3

Text-mined interactions from Literome

Burger et al., Oncogene 2005 (Cell Transformation, Neoplastic...) : In CXCR2 transfected NIH 3T3 cells and human microvascular endothelial cells ( HMEC ), which express the CXCR2 constitutively, STAT3 is phosphorylated upon stimulation with IL-8 ( CXCL8 )
Kanda et al., Endocrinology 2011 (Psoriasis) : This indicates the involvement of NF-?B in CXCL8, CXCL10, and CCL20 induction by visfatin and the involvement of STAT3 in CXCL8 induction
Pini et al., J Leukoc Biol 2012 (Inflammation...) : However, the delayed resolution of neutrophil infiltration ; sustained production of CXCL1, CXCL2 , and CCL2 ; prolonged activation of STAT-3 ; and induction of MMP-7 in the pancreas, as well as heightened induction of serum amylase A of DIO mice, were blunted significantly in DIO IL-6 KO mice
Nguyen-Jackson et al., J Leukoc Biol 2012 : Induction of Cxcl2 was regulated directly by G-CSF activated STAT3 via interaction at a STAT consensus element in the Cxcl2 promoter