Gene interactions and pathways from curated databases and text-mining

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INS — SYT1

Text-mined interactions from Literome

Iezzi et al., FEBS Lett 2005 : Adenovirus mediated silencing of synaptotagmin 9 inhibits Ca2+ dependent insulin secretion in islets
Dugo et al., Crit Care Med 2006 (Inflammation...) : In vitro, insulin or TDZD-8 caused similar reductions in the nuclear factor-kappaB p65 activity and similar increases in the phosphorylation of Ser9 of glycogen synthase kinase-3beta
Lalioti et al., Proc Natl Acad Sci U S A 2009 : The atypical kinase Cdk5 is activated by insulin , regulates the association between GLUT4 and E-Syt1 , and modulates glucose transport in 3T3-L1 adipocytes
Gustavsson et al., Diabetologia 2011 (Diabetes Mellitus, Type 2...) : Like insulin secretion from beta cells, glucagon secretion is dependent on calcium signals and a calcium sensing protein, synaptotagmin-7
Gustavsson et al., PloS one 2010 (Body Weight) : Neuronal calcium sensor synaptotagmin-9 is not involved in the regulation of glucose homeostasis or insulin secretion
Saleh et al., Exp Neurol 2013 (Diabetes Mellitus, Experimental...) : Exogenous insulin enhanced nuclear localization of p50 and c-rel but not p65 in diabetic neuronal cultures