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Text-mined interactions from Literome
Shibata et al., Anticancer Res 2000
(Liver Neoplasms, Experimental...) :
TAC-101 also
inhibited , in a concentration dependent manner, the binding of
AP-1 to its DNA binding sites present in the promoter region of the genes involved in the control of cell migration, invasion, and angiogenesis
Eshima et al., Tumour Biol 2009
(Carcinoma, Hepatocellular...) :
TAC-101 induced transcriptional activation of RAR, resulting in marked elevation of RARbeta, a representative retinoid response marker, and it also significantly
repressed the transcriptional activity of
AP-1 in JHH-7 cells ...
TAC-101 did not
inhibit AP-1 activity of the JHH-6 cell line, showing that AP-1 interference by TAC-101 must be in parallel with RAR activation
Murakami et al., Clin Exp Metastasis 1998
(Adenocarcinoma...) :
Furthermore,
TAC-101 inhibited the binding of
AP-1 to DNA on electrophoretic mobility shift assay using nuclear extract of AZ-521 cells, although ATRA did not inhibit