Gene interactions and pathways from curated databases and text-mining

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IL21 — TCF19

Text-mined interactions from Literome

McDermott et al., Trends Mol Med 2002 (Familial Mediterranean Fever...) : Disorders of interleukin-1 processing and of regulation of nuclear factor kappaB transcription factor , and possibly defective apoptosis, might be involved in the pathogenesis of all but one of these disorders
Wei et al., J Biol Chem 2007 : IL-21 also induces IL-17 production and expression of the transcription factor , RORgammat
Chen et al., Immunol Res 2008 (Bacterial Infections) : In the mouse, the differentiation of this new lineage is initiated by TGFbeta-1 and IL-6 and IL-21 , which activate Stat3 and induce the expression of the transcription factor retinoic acid related orphan receptor ( RORgammat )
Sheikh et al., Hepatology 2008 (Hepatitis C...) : This transcription factor plays a key role in the expression of cytokines, tumor necrosis factor alpha (TNF-alpha), interleukin 6, interleukin 8, tumor growth factor beta, and Fas ligand
Chen et al., Immunity 2008 (Arthritis, Rheumatoid...) : IRF-4 binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor ... IRF-4 binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor
Saraiva et al., Immunity 2009 : Interleukin-10 production by Th1 cells requires interleukin-12 induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose
Chen et al., J Immunol 2010 (Encephalomyelitis, Autoimmune, Experimental) : Regulation of the IL-21 gene by the NF-?B transcription factor c-Rel
Sung et al., J Biol Chem 1993 : Stimulation of interleukin-1 gene transcription may be caused by the stimulation of transcription factor activities, including those of AP-1, by these protein phosphatase inhibitors