Gene interactions and pathways from curated databases and text-mining

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HGF — TCF21

Text-mined interactions from Literome

Hanzawa et al., Carcinogenesis 2000 (Carcinoma, Squamous Cell...) : These results suggest that HGF induces expression of the Ets related E1AF transcription factor gene whose product in turn activates MMP genes and leads to oral cancer cell invasion
Abounader et al., J Neurochem 2001 (Glioblastoma) : SF/HGF induced the expression of c-fos and c-jun mRNA and increased the levels of AP-1 transcription factor in both cells lines as determined by AP-1-luciferase reporter expression
Recio et al., Oncogene 2002 (Melanoma) : We conclude that the ATF-2 transcription factor becomes activated by HGF/SF through p38 MAPK and SAPK/JNK
Paumelle et al., Oncogene 2002 (MAP Kinase Signaling System) : Hepatocyte growth factor/scatter factor activates the ETS1 transcription factor by a RAS-RAF-MEK-ERK signaling pathway
Cross et al., Placenta 2003 : Differentiation towards syncytiotrophoblast as well as the initiation of chorioallantoic ( villous ) morphogenesis is regulated by the Gcm1 transcription factor , and subsequent labyrinth development is dependent on Wnt, HGF and FGF signalling
Kaga et al., Vascul Pharmacol 2012 (Inflammation) : In addition, bFGF, but not HGF or VEGF, significantly activated an essential transcription factor for inflammation, NF?B, and gene expression of its downstream inflammation related cytokines ( IL-8 and MCP-1 ) in VSMCs, accompanied by an increase in the vascular permeability in the rat paper disc model
Lee et al., Oncol Res 2013 (Adenocarcinoma...) : We investigated the role of HGF induced activation of GRP and Ets-1 transcription factor in expression of the proangiogenic factor IL-8
Papkoff et al., Biochem Biophys Res Commun 1998 : Both Wnt-1 and HGF/SF lead to nuclear accumulation of beta-catenin and activation of a LEF/Tcf responsive reporter gene