Gene interactions and pathways from curated databases and text-mining

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PI3 — TCF3

Text-mined interactions from Literome

Lee et al., Mol Cancer Res 2004 (Breast Neoplasms...) : Stromal cell derived factor 1alpha ( SDF-1alpha ; CXCL12 ) stimulation of breast cancer cells resulted in phosphoinositide 3-kinase (PI-3K) activation, AKT phosphorylation, and activation of the FKHRL1 transcription factor
Huang et al., Chem Biol Interact 2009 (Glioma...) : Further ( Ac ) ( 5 ) GP also exerted an inhibitory effect on phosphoinositide 3-kinase (PI3K) protein expression, phosphorylation of extracellular signal regulated kinases 1 and 2 ( ERK1/2 ) and inhibition of activation of transcription factor nuclear factor kappa B (NF-kappaB), c-Fos, c-Jun
Yen et al., J Biol Chem 2011 (MAP Kinase Signaling System) : PKA, PI3K , and ERK inhibitors abolished PGE2- and cAMP induced c-Fos and MMP-9 up-regulation, and ERK activation was required for the binding of activator protein 1 (AP-1) transcription factor to the MMP-9 promoter