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EPHB2 — TFR2
Text-mined interactions from Literome
Calzolari et al., Blood Cells Mol Dis 2009
(Carcinoma...) :
In colon cancer cell lines,
TfR2 is localized in membrane lipid rafts,
induces ERK1/ERK2 phosphorylation, when activated by its ligand transferring, and is preferentially expressed during S-M phases of the cell cycle
Poli et al., Haematologica 2010
(Hemochromatosis...) :
We showed that the silencing of HFE and
transferrin receptor 2 reduced both
Erk phosphorylation and furin expression, that the exogenous expression of the two enhanced the induction of phosphoErk1/2 and furin by holotransferrin, but that this did not occur when the pathogenic HFE mutant C282Y was expressed