Gene interactions and pathways from curated databases and text-mining

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EPHB2 — TFR2

Text-mined interactions from Literome

Calzolari et al., Blood Cells Mol Dis 2009 (Carcinoma...) : In colon cancer cell lines, TfR2 is localized in membrane lipid rafts, induces ERK1/ERK2 phosphorylation, when activated by its ligand transferring, and is preferentially expressed during S-M phases of the cell cycle
Poli et al., Haematologica 2010 (Hemochromatosis...) : We showed that the silencing of HFE and transferrin receptor 2 reduced both Erk phosphorylation and furin expression, that the exogenous expression of the two enhanced the induction of phosphoErk1/2 and furin by holotransferrin, but that this did not occur when the pathogenic HFE mutant C282Y was expressed