Gene interactions and pathways from curated databases and text-mining

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CA2 — THBD

Text-mined interactions from Literome

Rezaie et al., J Biol Chem 1994 : Mutation of Glu-80 -- > Lys results in a protein C mutant that no longer requires Ca2+ for rapid activation by the thrombin-thrombomodulin complex
Rezaie et al., Eur J Biochem 1994 : The resultant mutants were still resistant to activation by thrombin, and still required Ca2+ for activation by thrombin-thrombomodulin complex
Raife et al., Blood 1996 : These results demonstrate that keratinocyte thrombomodulin is regulated by retinoids and Ca2+ , but not by TNF, and that regulation of thrombomodulin expression differs in keratinocytes and endothelial cells