Gene interactions and pathways from curated databases and text-mining

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MMP13 — TLR1

Text-mined interactions from Literome

West et al., J Cell Biol 2008 : Surprisingly, MMP inhibitors block TLR signaling induced podosome disassembly, although stimulated endocytosis is unaffected, which demonstrates that the two phenomena are not obligatorily coupled
Ospelt et al., Arthritis Rheum 2008 (Arthritis, Rheumatoid...) : Among the expressed TLRs, TLR-3 and TLR-4 were the most abundant in synovial fibroblasts, and stimulation of synovial fibroblasts with the TLR-3 ligand poly ( I-C ) led to the most pronounced increase in IL-6, MMP-3, and MMP-13