Gene interactions and pathways from curated databases and text-mining

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STAT1 — TLR7

Text-mined interactions from Literome

Rhee et al., J Biol Chem 2003 : TLR induced phosphorylation of Ser-727 STAT1 could be blocked by the selective p38 mitogen activated protein kinase inhibitor SB203580 ... Lastly, TLR4 induced activation of Ser-727 STAT1 phosphorylation could be blocked by rottlerin, a specific inhibitor of protein kinase C-delta
Shoenfelt et al., J Endotoxin Res 2006 : Unlike other cell types, the p38 mitogen activated protein kinase was necessary, but not sufficient, for TLR induced phosphorylation of Ser-727 STAT1 in macrophages
Rothlin et al., Cell 2007 (Inflammation) : TLR induction of IFNAR-STAT1 signaling upregulates the TAM system, which in turn usurps the IFNAR-STAT1 cassette to induce the cytokine and TLR suppressors SOCS1 and SOCS3
Thibault et al., J Clin Invest 2008 (Kidney Diseases...) : IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice
Tel et al., Cancer Immunol Immunother 2012 : Furthermore, oxaliplatin decreased TLR induced STAT1 and STAT3 expression, and NF-?B mediated responses