Gene interactions and pathways from curated databases and text-mining

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EMD — TNF

Text-mined interactions from Literome

He et al., Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005 : TNF-alpha increases cell death by approximately 2-fold, which is attenuated by both EMD and TGF-beta1
Myhre et al., J Periodontal Res 2006 : We found that EMD attenuated the release of TNF-alpha and interleukin-8 in whole blood from healthy donors challenged by lipopolysaccharide or peptidoglycan, while the release of interleukin-10 was unchanged
Gundersen et al., Surg Infect (Larchmt) 2008 (Disease Models, Animal...) : Recent investigations, showing that EMD inhibits the production of tumor necrosis factor-alpha (TNF-alpha) when added to human whole blood, indicate a novel role for EMD as a modulator of systemic inflammation