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IFNG — TP63

Text-mined interactions from Literome

Cowdery et al., J Immunol 1999 : Even though IFN-gamma augmented LPS-driven p40 promoter activity in RAW 264 cells, the combination of IFN-gamma and LPS induced less p40 mRNA or protein secretion than the combination of IFN-gamma and CpG DNA
Weinmann et al., Immunity 1999 : In primary macrophages, IFNgamma synergistically enhanced p40 expression, but little effect on remodeling or promoter occupancy was observed
Campbell et al., Eur J Immunol 2000 : Gal-lectin plus IFN-gamma stimulated IL-12 p40 and p35 gene transcription with stable mRNA transcripts and a differential requirement for protein synthesis
Németh et al., Biochim Biophys Acta 2001 : The effect of amiloride was post-transcriptional, as IL-12 p40 mRNA levels induced by lipopolysaccharide and interferon-gamma were not affected by this inhibitor
Costa et al., J Immunol 2001 (Encephalomyelitis, Autoimmune, Experimental) : In vitro analysis demonstrated that IL-12 p40 suppressed IFN-gamma production in developing and effector Th1 populations, indicating its potential to modulate Th1 promoted inflammation
Bastos et al., J Interferon Cytokine Res 2002 (Malaria...) : Taken together, our results support the idea that the absence of IL-12p40 not only affects IFN-gamma production but also has deep consequences in macrophage effector functions that may contribute to exacerbation of the early phase of P. c. chabaudi malaria
Zhu et al., J Biol Chem 2003 : In this study, a composite NFAT/ICSBP binding site at -68 to -54 is identified that is functionally important for p40 promoter activation by lipopolysaccharide (LPS) and LPS plus IFN-gamma
Pedra et al., FEMS Immunol Med Microbiol 2007 (Anaplasmosis...) : The lack of IL-12/23p40 reduced IFN-gamma production in both CD4 ( + ) and CD8 ( + ) T cells although the effect was more pronounced in CD4 ( + ) T cells
Yamauchi et al., International journal of biological sciences 2009 : AZM reduced the induction of IL-12p40 by LPS/IFN-gamma in a dose dependent manner
Ma et al., J Exp Med 1996 : Because the RAW264.7 cell line is easily transfectable and regulates the endogenous IL-12 p40 gene in response to IFN-gamma or LPS similarly to human monocytes, it was used for analysis of the regulation of the cloned human IL-12 p40 promoter
Snijders et al., J Immunol 1996 : We found that in LPS stimulated whole blood and purified monocytes, p70 and p40 production are enhanced by IFN-gamma and inhibited by IL-10 and IL-4
Ertel et al., Blood 1997 (Endotoxemia) : IFN-gamma dose-dependently ( P < .05 ) increased the release of IL-12 p40 and p70 into LPS stimulated whole blood from healthy humans without effect in whole blood from critically ill patients