UCSC Genome Browser Gene Interaction Graph

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

Gene interactions and pathways from curated databases and text-mining

◀ Back to TRAF5

TRAF3 — TRAF5

Pathways - manually collected, often from reviews:

BioCarta yaci and bcma stimulation of b cell immune responses: BCMA/TRAF6/TRAF5/TRAF3 complex (TNFRSF17-TRAF6-TRAF5-TRAF3) → APRIL (TNFSF13) (modification, collaborate)
BioCarta yaci and bcma stimulation of b cell immune responses: BCMA/TRAF6/TRAF5/TRAF3 complex (TNFRSF17-TRAF6-TRAF5-TRAF3) → APRIL/BCMA/TRAF6/TRAF5/TRAF3 complex (TNFRSF17-TRAF6-TRAF5-TRAF3-TNFSF13) (modification, collaborate)
BioCarta yaci and bcma stimulation of b cell immune responses: APRIL (TNFSF13) → APRIL/BCMA/TRAF6/TRAF5/TRAF3 complex (TNFRSF17-TRAF6-TRAF5-TRAF3-TNFSF13) (modification, collaborate)
BioCarta yaci and bcma stimulation of b cell immune responses: BAFF/BCMA/TRAF6/TRAF5/TRAF3 complex (TNFRSF17-TRAF6-TRAF5-TRAF3-TNFSF13B) → BCMA/TRAF6/TRAF5/TRAF3 complex (TNFRSF17-TRAF6-TRAF5-TRAF3) (modification, collaborate)
BioCarta yaci and bcma stimulation of b cell immune responses: BAFF/BCMA/TRAF6/TRAF5/TRAF3 complex (TNFRSF17-TRAF6-TRAF5-TRAF3-TNFSF13B) → BAFF (TNFSF13B) (modification, collaborate)
BioCarta yaci and bcma stimulation of b cell immune responses: BCMA/TRAF6/TRAF5/TRAF3 complex (TNFRSF17-TRAF6-TRAF5-TRAF3) → BAFF (TNFSF13B) (modification, collaborate)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Biogrid Interaction: TRAF3 — TRAF5 (direct interaction, fluorescent resonance energy transfer) He et al., J Biol Chem 2004 *
IRef Biogrid Interaction: TRAF3 — TRAF5 (physical association, affinity chromatography technology) Li et al., Immunity 2011
IRef Hprd Interaction: TRAF3 — TRAF5 (in vivo) Pullen et al., Biochemistry 1998
IRef Hprd Interaction: TRAF3 — TRAF5 (in vitro) Pullen et al., Biochemistry 1998

Text-mined interactions from Literome

Graham et al., J Immunol 2009 : LMP1 does n't induce TRAF degradation, and employs TRAF3 as a positive mediator of cell signaling, whereas CD40 signals are inhibited by TRAF3
Valente et al., Free Radic Biol Med 2013 : AOPP-MSA stimulated Nox2/Rac1 dependent superoxide generation, TRAF3IP2 expression, and TRAF3IP2 dependent JNK activation