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HSPG2 — TRPC3

Text-mined interactions from Literome

Venkatachalam et al., J Biol Chem 2003 : In both HEK293 cells and DT40 cells, TRPC5 and TRPC3 channel responses to PLC activation were highly analogous, but only TRPC3 and not TRPC5 channels responded to the addition of the permeant diacylglycerol ( DAG ) analogue, 1-oleoyl-2-acetyl-sn-glycerol ( OAG )
Lièvremont et al., Am J Physiol Cell Physiol 2004 (Calcium Signaling) : However, when stably expressed in HEK-293 cells, TRPC7 can be activated by either Ca ( 2+ ) store depletion or PLC activation
Tu et al., J Invest Dermatol 2005 : Here we investigate the role of phospholipase C (PLC) in regulation of native SOC and the expression of endogenous TRPC in human epidermal keratinocytes
Graziani et al., Biochem J 2006 (Calcium Signaling) : Promotion of TRPC3 membrane expression by cholesterol was persistent over 30 min, while PLC mediated enhancement of plasma membrane expression of TRPC3 was transient in nature
Roy et al., ACS Chem Biol 2006 : PLC can activate expression of surface transient receptor potential channels ( TRPC ) such as TRPC3, which modulate calcium entry through the plasma membrane
Horinouchi et al., J Pharmacol Sci 2011 : These results suggest that 1 ) TRPC3, TRPC5, TRPC6, and TRPC7 can function as ET ( A ) R-operated Ca ( 2+ ) channels ; 2 ) G ( q ) protein, PLC , and CaM are involved in TRPC3- and TRPC6 mediated ROCE ; 3 ) ET ( A ) R-mediated activation of TRPC3 and TRPC6 requires the CIRB domain ; and 4 ) abolition of ET ( A ) R-induced ROCE by CIRB domain deletion and CaM inhibition is due to loss of CaM binding to the channels but not loss of cell surface TRPC3 and TRPC6