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PTCH1 — TYR
Text-mined interactions from Literome
Warmka et al., Mol Cell Biol 2001
:
In contrast, overexpression of
PTC1 did not
inhibit phosphorylation of Hog1
Tyr in the phosphorylation lip, suggesting that Ptc1 does not act on Pbs2. Deletion of PTC1 also strongly affected Hog1, leading to high basal Hog1 activity and sustained Hog1 activity in response to osmotic stress, the latter being consistent with a role for Ptc1 in adaptation
Xing et al., J Biol Chem 1998
(Carcinoma, Papillary...) :
We also showed that
RET/PTC1 , 2A/RET, and 2B/RET induce ELK-, cAMP-responsive element binding protein ( CREB ), or JUN mediated gene expression in PC12 cells, and these three signaling events are
mediated by phosphorylated
Tyr294 and phosphorylated Tyr451 binding sites in RET/PTC1