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Kashishian et al., EMBO J 1992
(Chromosome Deletion) :
Mutagenesis studies show that Tyr740 and 751 are involved in the PDGF stimulated binding of phosphatidylinositol (PI) 3 kinase, and Tyr771 is required for efficient binding of GAP , the GTPase activator of Ras
Brott et al., Mol Cell Biol 1991
:
Therefore, our results suggest that both Tyr-527 phosphorylation and the SH2 region contribute to stable association of c-Src with GAP Lee et al., Am J Physiol 1997
:
Tyr kinase (TK) and 5-HT uptake inhibitors and 8-bromoadenosine 3',5'-cyclic monophosphate blocked both the 5-HT induced DNA synthesis and Tyr phosphorylation of GAP