Yang et al., Carcinogenesis 2008
:
Correspondingly, C/EBPalpha overexpression significantly inhibited the DNA binding ability of HIF-1 and expressions of hypoxia-responsive element-driven luciferase and HIF-1 targeted genes vascular endothelial growth factor , glucose transporter-1 and phosphoglycerate kinase 1
Montano et al., Circ Res 2008
(Heart Defects, Congenital) :
The basis for this role of HEXIM1 is that VEGF is a direct transcriptional target of HEXIM1, and involves attenuation a repressive effects of C/EBPalpha on VEGF gene transcription