Gene interactions and pathways from curated databases and text-mining

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HSP90AA1 — WEE1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

  • STRING interaction: HSP90AA1 — WEE1 (interaction, mapped from grid kegg_pathways)
  • STRING interaction: WEE1 — HSP90AA1 (interaction, mapped from grid kegg_pathways)

Text-mined interactions from Literome

Mollapour et al., Mol Cell 2010 : Swe1Wee1 dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function
Haarberg et al., Mol Cancer Ther 2013 (Melanoma) : In vitro, HSP90 inhibition led to the degradation of ARAF, CRAF, Wee1 , Chk1, and cdc2 and was associated with decreased mitogen activated protein kinase ( MAPK ), AKT, mTOR, and c-jun NH2 kinase ( JNK ) signaling