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FOS — WNK1

Text-mined interactions from Literome

Hsu et al., Cancer Res 2001 (Cell Transformation, Neoplastic) : Expression of a transactivation-deficient mutant of Jun or dominant negative extracellular signal regulated kinase suppressed both AP-1 activation and p65-specific transactivation in JB6 cells, suggesting that AP-1 activity is needed for p65 transactivation and consequently for NF-kappaB activation
Murakami et al., J Nutr 2005 (Neoplasms) : Pretreatment of RAW264.7 cells with LPS led to the activation of mitogen activated protein kinase ( MAPK ) s [ p38, extracellular signal regulated kinase ( ERK ) 1/2, c-Jun NH2-terminal kinase (JNK)1/2 ] and Akt, together with degradation of the inhibitor of nuclear factor-kappaB ( IkappaB)-alpha protein and nuclear translocation of nuclear factor (NF)-kappaB p65 , and the resultant activation of activator protein (AP)-1 , NF-kappaB, and cAMP-responsive element binding protein ( CREB ) transcription factors
La et al., J Periodontol 2009 : The suppression of MMP secretion was associated with inhibition of NF-kappaB p65 and AP-1 activation
Yang et al., J Cell Physiol 2010 (Arthritis, Rheumatoid) : IL-1beta induced ICAM-1 expression, extracellular signal regulated kinase ( ERK ) and c-Jun-N-terminal kinase (JNK) phosphorylation, AP-1 activation, and nuclear factor-kappaB (NF-kappaB) p65 translocation were attenuated by the inhibitors of MEK1/2 ( U0126 ), JNK ( SP600125 ), AP-1 ( tanshinone IIA ), and NF-kappaB ( helenalin ) or transfection with respective short hairpin RNA plasmids