Gene interactions and pathways from curated databases and text-mining

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FOXO1 — WNT1

Text-mined interactions from Literome

Wang et al., Clin Cancer Res 2009 (Endometrial Neoplasms) : Progesterone induction of DKK1 and FOXO1 results in inhibition of Wnt signaling in the human endometrium
Manolopoulos et al., Mol Psychiatry 2010 (Alzheimer Disease...) : Wnt inhibition may also result in a sustained activation of FoxO proteins with induction of apoptosis and neuronal loss, thereby completing a vicious circle from oxidative stress, InsRes and hyperglycaemia back to the formation of ROS and consecutive neurodegeneration
Chong et al., Curr Neurovasc Res 2011 (Diabetes Mellitus, Experimental...) : EPO relies upon novel signaling of Wnt1 that requires Akt1, FoxO3a , GSK-3ß, and ß-catenin to foster vascular integrity during experimental diabetes
Dieudonné et al., J Bone Miner Res 2012 (Bone Neoplasms...) : Doxorubicin modulated Foxo3a binding on syndecan-2 gene promoter and induced Foxo dependent inhibition of Wnt/TCF activity