Gene interactions and pathways from curated databases and text-mining

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CDC42 — WNT11

Text-mined interactions from Literome

Penzo-Mendèz et al., Dev Biol 2003 : In order to provide data concerning the molecular targets of Wnt-11/Xfz7 signals, we have analyzed the regulation of the Rho GTPase Cdc42 by Wnt-11
Shutes et al., Methods Enzymol 2006 : Wrch-1 ( Wnt regulated Cdc42 homolog-1 ) and the closely related Chp ( Cdc42 homologous protein ) /Wrch-2 protein comprise a distinct branch of the mammalian Rho GTPase family
Mezzacappa et al., Methods Mol Biol 2012 : The Rho family of small GTPases are activated and required for non-canonical Wnt signaling during gastrulation, and in this chapter, we describe biochemical assays for the detection of Wnt mediated activation of Rho, Rac, and Cdc42 in both mammalian cells and Xenopus embryo explants