Gene interactions and pathways from curated databases and text-mining

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IL6 — XRCC1

Text-mined interactions from Literome

Koo et al., Cancer Immunol Immunother 1992 (Carcinoma, Renal Cell...) : We investigated the production of IL-6 by renal cell cancer (RCC) and the growth effects of IL-6 on RCC ... The growth effects of IL-6 on RCC were also investigated in two experimental systems : IL-6 was found to stimulate proliferative responses in six of six RCC tumor lines as measured by thymidine-uptake assays ; however, only one of six tumor lines displayed an increase in proliferative response of greater than 21 % ( 113 % )
Chang et al., Anticancer Res 1997 (Kidney Neoplasms) : The role and induction parameters of IL-6 in renal cell carcinoma (RCC) are not fully understood
Honma et al., J Oral Pathol Med 1998 (Radicular Cyst) : In vitro analysis indicated dose dependent release of both IL-6 and IL-8 by HGFs in response to RCC ... Furthermore, anti-IL-1beta antibody ( neutralization test ) did not prevent the stimulation of IL-6 release by RCC