Gene interactions and pathways from curated databases and text-mining
IRF6: top 25 interacting genes (chr1:209958967-209979520)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IRF6-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IRF6, not among the Top 25
Other genes interacting with IRF6. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

MAPK6 ▸ MAPK7 ▸ IFNG ▸ EPHB2 ▸ NFKBIA ▸ CCL2 ▸ NOS1 ▸
CD14 ▸ ICAM1 ▸ CPOX ▸ IL4 ▸ JUN ▸ IL18 ▸ IL2 ▸
NOS3 ▸ IL5 ▸ IL13 ▸ FOS ▸ PTBP1 ▸ PTBP2 ▸ HNRNPH1 ▸
HNRNPF ▸ IL3 ▸ IL33 ▸ IL15 ▸ IL21 ▸ IL32 ▸ IL37 ▸
IL19 ▸ IL24 ▸ IL11 ▸ IL9 ▸ IL7 ▸ IL16 ▸ IL22 ▸
IL31 ▸ IL20 ▸ IL25 ▸ IL26 ▸ IL27 ▸ IL34 ▸ TLR2 ▸
CSF2 ▸ MMP9 ▸ AKT1 ▸ AKT2 ▸ SYT1 ▸ AHSA1 ▸ AKT3 ▸
CASP3 ▸ CASP1 ▸ CXCL10 ▸ CASP4 ▸ CASP6 ▸ CASP9 ▸ CASP8 ▸
CASP12 ▸ CASP10 ▸ CASP16 ▸ CASP2 ▸ CASP14 ▸ CASP5 ▸ CASP7 ▸
IFNB1 ▸ VCAM1 ▸ IL1RN ▸ RNF19A ▸ GRAP2 ▸ UMOD ▸ WNK1 ▸
LBP ▸ SELE ▸ TLR3 ▸ TLR9 ▸ HMOX1 ▸ TLR1 ▸ CCL3 ▸
VEGFA ▸ ANXA6 ▸ CFP ▸ TLR7 ▸ CRK ▸ TLR6 ▸ LANCL1 ▸
TLR8 ▸ TLR5 ▸ MMP2 ▸ CD86 ▸ GPI ▸ TLR10 ▸ STAT1 ▸
CD79A ▸ CD40 ▸ HMGB1 ▸ MMP1 ▸ MPO ▸ NOX1 ▸ CHUK ▸
ITGAM ▸ IKBKB ▸ CD80 ▸ POLDIP2 ▸ IRF3 ▸ STAT3 ▸ MIP ▸
NOX4 ▸ MMP3 ▸ MYD88 ▸ MMP13 ▸ TP63 ▸ NOX3 ▸ NOX5 ▸
MUC1 ▸ MUC2 ▸ CA2 ▸ MMP8 ▸ TGFB1 ▸ MMP14 ▸ MMP11 ▸
CXCL1 ▸ IRAK1 ▸ MMP12 ▸ MUC7 ▸ MMP25 ▸ MMP27 ▸ MUC16 ▸
CD46 ▸ MMP21 ▸ MUC4 ▸ CXCL2 ▸ RABEPK ▸ MMP20 ▸ MMP7 ▸
MMP17 ▸ MMP16 ▸ MMP19 ▸ MMP15 ▸ MMP28 ▸ MMP26 ▸ MMP24 ▸
MMP10 ▸ CXCL9 ▸ IKBKG ▸ TCF21 ▸ MUC19 ▸ MUC15 ▸ MUC12 ▸
TCF19 ▸ TCF12 ▸ TCF7 ▸ TCF24 ▸ TCF20 ▸ TCF23 ▸ MUC21 ▸
TCF3 ▸ MUC22 ▸ MUC8 ▸ TCF15 ▸ MUC20 ▸ TCF4 ▸ MUC6 ▸
TCF25 ▸ MUC17 ▸ MUC13 ▸ CXCL11 ▸ SERPINE1 ▸ PAF1 ▸ CXCL12 ▸
WDR61 ▸ LYZ ▸ LEO1 ▸ CTR9 ▸ HLA-DRA ▸ CDC73 ▸ PTGS1 ▸
CXCL13 ▸ IRF1 ▸ PLA2G4A ▸ CXCL5 ▸ LEP ▸ HLA-DRB1 ▸ CXCL16 ▸
IRAK4 ▸ CSF3 ▸ ITGB2 ▸ SOD2 ▸ CXCL6 ▸ MIPEP ▸ SOD1 ▸
C1orf228 ▸ SOD3 ▸ IL23A ▸ CXCL17 ▸ IDO1 ▸ CXCL3 ▸ PI3 ▸
CXCL14 ▸ PGF ▸ HDC ▸ PIK3R1 ▸ PIK3CA ▸ CRH ▸ REL ▸
HGF ▸ PDCD11 ▸ SLC25A10 ▸ LTB ▸ CSF1 ▸ PLA2G1B ▸ IRAK3 ▸
SAA1 ▸ MYLIP ▸ CD83 ▸ SOCS3 ▸ EGR1 ▸ ICAM5 ▸ NM ▸
ICAM3 ▸ ICAM2 ▸ ICAM4 ▸ NANOS2 ▸ MUC5AC ▸ IRAK2 ▸ INS ▸
FAS ▸ ARG1 ▸ NUP43 ▸ IGF1 ▸ PTGES ▸ SLPI ▸ TBCE ▸
SOAT1 ▸ CCR2 ▸ TNPO1 ▸ EDN1 ▸ BPI ▸ TNFSF11 ▸ CD4 ▸
SETD2 ▸ MIF ▸ CEBPB ▸ DEFB4B ▸ HDAC1 ▸ CREB5 ▸ CEBPA ▸
CREB1 ▸ CREB3 ▸ DUSP1 ▸ FASLG ▸ NCF1 ▸ CAT ▸ IRF7 ▸
CCL4 ▸ S100A12 ▸ IFI44 ▸ SRC ▸ MDM1 ▸ ARF6 ▸ CRP ▸
MDM4 ▸ CD69 ▸ HDAC2 ▸ SELP ▸ PTX3 ▸ CCL20 ▸ ARF4 ▸
MDM2 ▸ IRF2 ▸ MAP3K8 ▸ ARF3 ▸ ARF5 ▸ ARF1 ▸ CCR7 ▸
GP9 ▸ ARG2 ▸ TNFRSF11B ▸ PLD5 ▸ IRF8 ▸ RBBP4 ▸ GP2 ▸
RHOA ▸ PLD4 ▸ APOE ▸ RAC1 ▸ HIF1A ▸ NFKBIB ▸ PPARG ▸
GP5 ▸ PLD6 ▸ PLD1 ▸ ABCC1 ▸ MTOR ▸ SLC17A5 ▸ IRF4 ▸
NGF ▸ GP6 ▸ CISH ▸ PLD2 ▸ PLG ▸ PLD3 ▸ CCL5 ▸
TRAF6 ▸ AVP ▸ PGD ▸ BAX ▸ AGTR2 ▸ CDCA5 ▸ CD40LG ▸
ALB ▸ APOB ▸ CCR5 ▸ NOD2 ▸ SERPINB2 ▸ PRKCA ▸ TREM1 ▸
CORT ▸ PPARA ▸ IL17D ▸ MAPKAPK2 ▸ SP1 ▸ ADAM11 ▸ HBD ▸
ZFP36 ▸ GJA1 ▸ GIT2 ▸ TIMP1 ▸ BCL2 ▸ JAK2 ▸ BDNF ▸
CCND1 ▸ APC ▸ AHR ▸ LITAF ▸ LPL ▸ HSPG2 ▸ LIF ▸
F3 ▸ ATP5O ▸ LY96 ▸ PDE4B ▸ TBK1 ▸ BCL10 ▸ IRF5 ▸
IRF9 ▸ IL1R1 ▸ PLAU ▸ IL2RA ▸ CAV1 ▸ LTF ▸ GNRH1 ▸
EGFR ▸ LYN ▸ STS ▸ SELL ▸ CALM3 ▸ RBBP7 ▸ IFNA4 ▸
LCN2 ▸ ATF2 ▸ CXCR4 ▸ FCER2 ▸ ODC1 ▸ CCR3 ▸ SLC27A5 ▸
ATP8A2 ▸ P2RX7 ▸ MOCOS ▸ PRDX2 ▸ ADM ▸ UCN ▸ BTK ▸
PRL ▸ TFPI ▸ PARP1 ▸ RAF1 ▸ GDNF ▸ SPP1 ▸ SOCS1 ▸
NCF2 ▸ EIF2AK2 ▸ CSRP1 ▸ HSPD1 ▸ MNAT1 ▸ SIN3A ▸ PTK7 ▸
SAP130 ▸ PTK6 ▸ TNFSF13B ▸ MLYCD ▸ CCR6 ▸ IL17A ▸ TNFSF10 ▸
CYP3A ▸ SUDS3 ▸ CD2 ▸ PTK2 ▸ ARID4B ▸ BCL3 ▸ MT3 ▸
GAL ▸ IFNA2 ▸ AGTR1 ▸ NA ▸ SAP30 ▸ IFNA6 ▸ NOTCH1 ▸
IFNA7 ▸ IFNA8 ▸ CD8A ▸ SPHK1 ▸ PHKA2 ▸ ECM1 ▸ CXCR1 ▸
ACP2 ▸ ETS2 ▸ CD44 ▸ FGB ▸ IFNA21 ▸ PRG2 ▸ JAK1 ▸
CCR1 ▸ ECM2 ▸ CRAT ▸ LIPA ▸ GCHFR ▸ IFNA16 ▸ CCR4 ▸
CSE ▸ CD276 ▸ IFNA14 ▸ IFNA10 ▸ RELB ▸ APP ▸ CCR9 ▸
STAT5A ▸ MAP2K1 ▸ SETBP1 ▸ TP53 ▸ TGFB2 ▸ CEBPD ▸ IFNA1 ▸
PRG4 ▸ LDLR ▸ SLC22A3 ▸ NLRP3 ▸ RETN ▸ IFNA17 ▸ IFNA5 ▸
MAP3K14 ▸ NEDD9 ▸ IKBKAP ▸ ACE ▸ PRG3 ▸ MOK ▸ CEL ▸
ADAM17 ▸ IL2RB ▸ MSH3 ▸ CCR10 ▸ IFNA13 ▸ CCR8 ▸ ANXA1 ▸
PCBD1 ▸ EIF4EBP1 ▸ TRAM1 ▸ SH3D19 ▸ ALG1 ▸ NOD1 ▸ HDAC3 ▸
TXN ▸ CAV3 ▸ TNP1 ▸ MSH6 ▸ THBD ▸ NOTCH2 ▸ APCS ▸
TF ▸ CD55 ▸ CRYGEP ▸ BCL6 ▸ SAA4 ▸ CCL24 ▸ GHR ▸
TYK2 ▸ CADM1 ▸ WAS ▸ CAMP ▸ F2R ▸ MSH4 ▸ PLIN2 ▸
BCL9 ▸ PAM ▸ NOTCH3 ▸ PLAUR ▸ CXCR2 ▸ TRAM2 ▸ OCLN ▸
SAA2 ▸ EDN3 ▸ NOTCH4 ▸ MAF ▸ SLCO6A1 ▸ TNFRSF1B ▸ OLR1 ▸
ABCB1 ▸ MSH5 ▸ HDAC11 ▸ C9orf3 ▸ MSH2 ▸ SYK ▸ RAC2 ▸
UCP2 ▸ NEU1 ▸ TNFRSF1A ▸ ATF3 ▸ IGFBP3 ▸ S100A8 ▸ LTA ▸
PTPN11 ▸ FBXO32 ▸ ABCA1 ▸ F2RL1 ▸ SIGLEC7 ▸ TGFB3 ▸ SERPING1 ▸
TNP2 ▸ EDN2 ▸ BCL5 ▸ GIF ▸ CNR2 ▸ PRKAB1 ▸ HP ▸
SMC6 ▸ LOX ▸ PRKAB2 ▸ TRAF1 ▸ PRKAA2 ▸ GPX7 ▸ VIPR1 ▸
EPB42 ▸ JAK3 ▸ GPX4 ▸ NEU2 ▸ FXR2 ▸ SEC14L2 ▸ TYR ▸
CIITA ▸ S12 ▸ COA4 ▸ PTX4 ▸ ARC ▸ ACHE ▸ FADD ▸
GPX3 ▸ JUND ▸ CD1A ▸ PRDX1 ▸ MTA2 ▸ ACO1 ▸ MT4 ▸
TSPO ▸ ALPI ▸ SCARB1 ▸ ISG15 ▸ ANXA5 ▸ GFAP ▸ CCND2 ▸
CD38 ▸ S11 ▸ CAV2 ▸ NPY4R ▸ SMC2 ▸ NAALADL1 ▸ TOLLIP ▸
POU2F2 ▸ CDC42 ▸ POMC ▸ ITGAX ▸ SLC7A2 ▸ ELAVL1 ▸ CTSB ▸
GPX1 ▸ RPTOR ▸ CTLA4 ▸ NPPA ▸ OXTR ▸ COA1 ▸ LPO ▸
JUNB ▸ PGP ▸ COA6 ▸ NEU3 ▸ EIF4E ▸ SLC2A1 ▸ GPX2 ▸
MARCKS ▸ AGXT ▸ CYBB ▸ CES1 ▸ FPR1 ▸ SMC3 ▸ SMC5 ▸
A2M ▸ S7 ▸ CD19 ▸ DDIT3 ▸ GATA3 ▸ ICOSLG ▸ GPX8 ▸
UBL3 ▸ NEU4 ▸ HDAC6 ▸ PPARGC1A ▸ CCL18 ▸ CTRL ▸ COA3 ▸
BIRC3 ▸ CNP ▸ TECR ▸ PRKAG1 ▸ CHD4 ▸ AQP5 ▸ PLCG1 ▸
PRKAA1 ▸ PLTP ▸ PLAT ▸ SIGIRR ▸ SMC4 ▸ CX3CL1 ▸ PGC ▸
DDX58 ▸ MET ▸ FXR1 ▸ GSK3B ▸ GPX6 ▸ HMGCR ▸ VIP ▸
MAP3K7 ▸ PRKAG2 ▸ UPK3B ▸ CYP2B6 ▸ CD8B ▸ STX1A ▸ GAST ▸
MRXS5 ▸ IFIT2 ▸ GPX5 ▸ ADCY9 ▸ FGFR3 ▸ TFRC ▸ CETP ▸
CD28 ▸ WNT2 ▸ GATA2 ▸ GIT1 ▸ CDH13 ▸ CEBPZ ▸ COA5 ▸
PPP2R2B ▸ C4BPA ▸ MTA1 ▸ KCNMA1 ▸ RHO ▸ PRKAR2B ▸ ERP27 ▸
STAR ▸ ERP29 ▸ NCOR1 ▸ HDAC9 ▸ SIRT1 ▸ FPR2 ▸ USP14 ▸
F12 ▸ P2RX4 ▸ PDCD1LG2 ▸ MBD3 ▸ CX3CR1 ▸ VDR ▸ MAL ▸
IFN1@ ▸ AQP4 ▸ IRG1 ▸ PECAM1 ▸ SPAG8 ▸ VWF ▸ MAP2K2 ▸
MCM2 ▸ CYP4F22 ▸ TNFSF13 ▸ LAMP1 ▸ RHOB ▸ CAPN6 ▸ CPP ▸
PPP2CA ▸ KHSRP ▸ IL1R2 ▸ CES2 ▸ APOA1 ▸ HPGDS ▸ CAPN3 ▸
ACSL1 ▸ NQO1 ▸ GATA4 ▸ ABL1 ▸ NDUFAB1 ▸ QRICH1 ▸ USP7 ▸
PARP16 ▸ AQP8 ▸ AGT ▸ PLEK ▸ ADCY6 ▸ AKT1S1 ▸ PRKACB ▸
SERPINB6 ▸ PGR ▸ TPGS1 ▸ PMPCB ▸ CORO2A ▸ CTNNB1 ▸ PKD2 ▸
SLC5A1 ▸ PRDX5 ▸ C5AR1 ▸ ADCY4 ▸ CAPN15 ▸ QRICH2 ▸ GATA1 ▸
TPX2 ▸ OSM ▸ NR4A1 ▸ CYP4F2 ▸ CD9 ▸ FOSL1 ▸ PRTN3 ▸
PKD3 ▸ BDKRB1 ▸ EPS8 ▸ LRP1 ▸ PLCG2 ▸ TRIM63 ▸ NCF4 ▸
PARP10 ▸ MT-CYB ▸ CADM3 ▸ SPHK2 ▸ PRKAR2A ▸ LAMP2 ▸ PARP15 ▸
RIPK2 ▸ CYP4F12 ▸ RPS6KB1 ▸ IL1RAP ▸ PLN ▸ TAT ▸ LAMP5 ▸
IKBKE ▸ SDC2 ▸ LAMP3 ▸ LGALS1 ▸ CYP1A1 ▸ CAPN8 ▸ AQP2 ▸
CCL1 ▸ TPO ▸ BCAP31 ▸ GATA5 ▸ IL18BP ▸ ASS1 ▸ CAPN1 ▸
GSR ▸ ITGAL ▸ REG3A ▸ SP100 ▸ PARP3 ▸ PRKAR1A ▸ CES3 ▸
CROT ▸ NR1I2 ▸ NFKBIZ ▸ SREBF1 ▸ HDAC4 ▸ GLA ▸ ADCY10 ▸
ADCY2 ▸ FGF21 ▸ MCM3 ▸ FST ▸ MCM5 ▸ SMAD4 ▸ ITGB1 ▸
PRX ▸ C1QA ▸ ERF ▸ CYP1A2 ▸ TIMP3 ▸ BCR ▸ CAPN2 ▸
MAP2K3 ▸ PARP12 ▸ TUBGCP2 ▸ PRKCB ▸ GPS2 ▸ CAPN13 ▸ C1QB ▸
KITLG ▸ IL13RA1 ▸ EDNRA ▸ MST1R ▸ ACAN ▸ CAPN12 ▸ NTRK1 ▸
GATA6 ▸ PDGFB ▸ CAPN5 ▸ MUC5B ▸ SLC9A1 ▸ CAPN7 ▸ NPR1 ▸
MCM6 ▸ CD1D ▸ EPS15 ▸ FGF2 ▸ AQP1 ▸ CADM2 ▸ PARP6 ▸
PARP11 ▸ TBL1X ▸ FGF9 ▸ WNT5A ▸ PRKACG ▸ CTSL ▸ TPGS2 ▸
PTEN ▸ ELANE ▸ MICE ▸ HDAC10 ▸ ADCY1 ▸ SMAD7 ▸ NANOS1 ▸
PDGFA ▸ LGALS3 ▸ TXNRD2 ▸ GALT ▸ CAPN11 ▸ ERP44 ▸ CADM4 ▸
MCM7 ▸ PLA2G7 ▸ ADCY5 ▸ CNR1 ▸ FOXP3 ▸ HDAC7 ▸ PARP8 ▸
EPB41 ▸ PARP14 ▸ MARCO ▸ FCGR1A ▸ HSP90AA1 ▸ DST ▸ CD5 ▸
CAPN14 ▸ SMN1 ▸ PKD1 ▸ IL6R ▸ TFAP2A ▸ MLST8 ▸ PIR ▸
S1PR1 ▸ ADCY7 ▸ MEPE ▸ NTF3 ▸ CYP4F11 ▸ PARP4 ▸ SST ▸
S100A9 ▸ CAPN9 ▸ PPARD ▸ MCM4 ▸ PARP2 ▸ CD58 ▸ ETS1 ▸
PARP9 ▸ CLDN1 ▸ MCOLN1 ▸ TBL1XR1 ▸ CCL4L2 ▸ MAP2K6 ▸ KCNH4 ▸
NPY ▸ SDC4 ▸ HCLS1 ▸ RNPEP ▸ ESAM ▸ FMR1 ▸ FEV ▸
PRKAR1B ▸ INSR ▸ KLF4 ▸ KLK3 ▸ IGH ▸ SLC11A2 ▸ CAPN10 ▸
HAMP ▸ CPZ ▸ PRDM1 ▸ PDCD2 ▸ CLU ▸ CYP4F3 ▸ HDAC5 ▸
AMBP ▸ ISG20 ▸ ADCY3 ▸ IDS ▸ PPP2R1A ▸ S1PR3 ▸ MCS ▸
DOK3 ▸ IL2RG ▸ RSAD2 ▸ PVR ▸ RASIP1 ▸ PTHLH ▸ ADCY8 ▸
MTDH ▸ CYP4F8 ▸ HDAC8 ▸ ADAMTS5 ▸ G6PD ▸ LTC4S ▸ GTF3A ▸
UBC ▸ SMARCD1 ▸ COPS5 ▸ PCAF ▸ TAF1 ▸ NR3C1 ▸ ARHGAP29 ▸
ONECUT1 ▸ COPS2 ▸ TLX2 ▸ COPS4 ▸ ZBTB3 ▸ MID1 ▸ GTF2A1 ▸
CREBBP ▸ GTF2E1 ▸ CDK4 ▸ BNC2 ▸ GPS1 ▸ COPS6 ▸ RFX3 ▸
Data information
Please see the Gene Interactions Track Manual.