Gene interactions and pathways from curated databases and text-mining
IRF6: top 25 interacting genes (chr1:209958967-209979520)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IRF6-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IRF6, not among the Top 25
Other genes interacting with IRF6. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

MAPK7 ▸ MAPK6 ▸ IFNG ▸ EPHB2 ▸ NFKBIA ▸ NOS1 ▸ CCL2 ▸
CD14 ▸ ICAM1 ▸ CPOX ▸ IL4 ▸ JUN ▸ IL18 ▸ IL2 ▸
NOS3 ▸ IL5 ▸ IL13 ▸ FOS ▸ PTBP1 ▸ PTBP2 ▸ HNRNPH1 ▸
HNRNPF ▸ IL3 ▸ IL33 ▸ IL15 ▸ IL32 ▸ IL19 ▸ IL21 ▸
IL37 ▸ IL11 ▸ IL24 ▸ IL20 ▸ IL9 ▸ IL22 ▸ IL31 ▸
IL16 ▸ IL7 ▸ IL25 ▸ IL26 ▸ IL27 ▸ IL34 ▸ TLR2 ▸
CSF2 ▸ MMP9 ▸ AKT1 ▸ AKT2 ▸ SYT1 ▸ AKT3 ▸ AHSA1 ▸
CASP1 ▸ CASP3 ▸ CXCL10 ▸ CASP8 ▸ CASP9 ▸ CASP4 ▸ CASP6 ▸
CASP5 ▸ CASP12 ▸ CASP16 ▸ CASP2 ▸ CASP14 ▸ CASP7 ▸ CASP10 ▸
IFNB1 ▸ VCAM1 ▸ IL1RN ▸ RNF19A ▸ GRAP2 ▸ UMOD ▸ WNK1 ▸
LBP ▸ SELE ▸ TLR3 ▸ TLR9 ▸ HMOX1 ▸ CCL3 ▸ TLR1 ▸
VEGFA ▸ ANXA6 ▸ TLR7 ▸ CFP ▸ CRK ▸ TLR8 ▸ TLR6 ▸
TLR5 ▸ LANCL1 ▸ TLR10 ▸ GPI ▸ CD86 ▸ STAT1 ▸ MMP2 ▸
CD79A ▸ CD40 ▸ MMP1 ▸ HMGB1 ▸ MPO ▸ NOX1 ▸ CHUK ▸
ITGAM ▸ IKBKB ▸ POLDIP2 ▸ CD80 ▸ IRF3 ▸ STAT3 ▸ NOX4 ▸
MIP ▸ MYD88 ▸ MMP3 ▸ TP63 ▸ MMP13 ▸ MUC1 ▸ MUC2 ▸
NOX5 ▸ NOX3 ▸ MMP8 ▸ CA2 ▸ MMP14 ▸ TGFB1 ▸ IRAK1 ▸
CXCL1 ▸ MMP12 ▸ MUC7 ▸ MMP11 ▸ MMP27 ▸ CD46 ▸ RABEPK ▸
MMP19 ▸ MMP24 ▸ MMP16 ▸ MMP25 ▸ MMP7 ▸ MMP21 ▸ MMP28 ▸
MMP17 ▸ MMP15 ▸ MMP26 ▸ MMP20 ▸ MMP10 ▸ CXCL2 ▸ MUC4 ▸
MUC16 ▸ IKBKG ▸ TCF12 ▸ TCF3 ▸ MUC17 ▸ TCF15 ▸ MUC8 ▸
MUC15 ▸ TCF23 ▸ MUC19 ▸ MUC6 ▸ TCF24 ▸ MUC22 ▸ MUC13 ▸
TCF21 ▸ CXCL9 ▸ MUC21 ▸ TCF20 ▸ TCF4 ▸ MUC12 ▸ MUC20 ▸
TCF7 ▸ TCF19 ▸ TCF25 ▸ HLA-DRA ▸ CTR9 ▸ PAF1 ▸ CXCL12 ▸
CDC73 ▸ WDR61 ▸ LEO1 ▸ LYZ ▸ CXCL11 ▸ SERPINE1 ▸ PLA2G4A ▸
PTGS1 ▸ CXCL13 ▸ LEP ▸ CXCL5 ▸ HLA-DRB1 ▸ IRF1 ▸ MIPEP ▸
SOD3 ▸ ITGB2 ▸ CXCL16 ▸ CSF3 ▸ SOD2 ▸ CXCL6 ▸ IRAK4 ▸
C1orf228 ▸ SOD1 ▸ IDO1 ▸ PGF ▸ CXCL17 ▸ PI3 ▸ CXCL3 ▸
CXCL14 ▸ IL23A ▸ CRH ▸ REL ▸ HDC ▸ PIK3R1 ▸ PIK3CA ▸
PDCD11 ▸ HGF ▸ SAA1 ▸ MYLIP ▸ EGR1 ▸ PLA2G1B ▸ LTB ▸
SOCS3 ▸ CD83 ▸ CSF1 ▸ IRAK3 ▸ SLC25A10 ▸ ICAM5 ▸ ICAM4 ▸
ICAM3 ▸ ICAM2 ▸ NANOS2 ▸ NM ▸ IRAK2 ▸ INS ▸ MUC5AC ▸
FAS ▸ NUP43 ▸ ARG1 ▸ IGF1 ▸ PTGES ▸ SETD2 ▸ EDN1 ▸
MIF ▸ SOAT1 ▸ TNFSF11 ▸ CD4 ▸ SLPI ▸ CEBPB ▸ BPI ▸
TBCE ▸ TNPO1 ▸ CCR2 ▸ DEFB4B ▸ DUSP1 ▸ CEBPA ▸ CREB5 ▸
FASLG ▸ NCF1 ▸ HDAC1 ▸ IRF7 ▸ CAT ▸ CREB3 ▸ CCL4 ▸
CREB1 ▸ ARF3 ▸ ARF6 ▸ CCL20 ▸ MDM1 ▸ IRF2 ▸ CD69 ▸
MDM4 ▸ SELP ▸ ARF1 ▸ MDM2 ▸ S100A12 ▸ MAP3K8 ▸ ARF5 ▸
CRP ▸ HDAC2 ▸ ARF4 ▸ PTX3 ▸ IFI44 ▸ SRC ▸ PLD1 ▸
IRF4 ▸ PLD2 ▸ CISH ▸ CCR7 ▸ PLD5 ▸ PLD4 ▸ RAC1 ▸
TNFRSF11B ▸ NFKBIB ▸ RHOA ▸ IRF8 ▸ PPARG ▸ MTOR ▸ GP9 ▸
GP2 ▸ ABCC1 ▸ PLD3 ▸ GP5 ▸ GP6 ▸ RBBP4 ▸ SLC17A5 ▸
APOE ▸ PLD6 ▸ NGF ▸ HIF1A ▸ ARG2 ▸ PLG ▸ ALB ▸
AVP ▸ PRKCA ▸ CDCA5 ▸ CCL5 ▸ AGTR2 ▸ PGD ▸ APOB ▸
BAX ▸ TRAF6 ▸ CCR5 ▸ NOD2 ▸ CD40LG ▸ SERPINB2 ▸ CORT ▸
JAK2 ▸ HBD ▸ IL17D ▸ PPARA ▸ TREM1 ▸ GIT2 ▸ AHR ▸
MAPKAPK2 ▸ GJA1 ▸ ZFP36 ▸ BDNF ▸ CCND1 ▸ BCL2 ▸ TIMP1 ▸
APC ▸ SP1 ▸ ADAM11 ▸ CALM3 ▸ LY96 ▸ EGFR ▸ IRF5 ▸
CAV1 ▸ HSPG2 ▸ BCL10 ▸ IFNA4 ▸ SELL ▸ GNRH1 ▸ IL1R1 ▸
PDE4B ▸ PLAU ▸ F3 ▸ FCER2 ▸ LYN ▸ LCN2 ▸ IL2RA ▸
TBK1 ▸ LITAF ▸ IRF9 ▸ STS ▸ ATP5O ▸ LTF ▸ CXCR4 ▸
LIF ▸ ATF2 ▸ LPL ▸ ODC1 ▸ RBBP7 ▸ EIF2AK2 ▸ MLYCD ▸
SPP1 ▸ SAP130 ▸ PTK2 ▸ IL17A ▸ CYP3A ▸ MT3 ▸ TNFSF10 ▸
TNFSF13B ▸ PRDX2 ▸ ATP8A2 ▸ SLC27A5 ▸ PTK7 ▸ UCN ▸ P2RX7 ▸
SIN3A ▸ CD2 ▸ CCR3 ▸ GDNF ▸ CCR6 ▸ PARP1 ▸ BTK ▸
SUDS3 ▸ NA ▸ HSPD1 ▸ SAP30 ▸ NCF2 ▸ ARID4B ▸ CSRP1 ▸
AGTR1 ▸ IFNA2 ▸ TFPI ▸ RAF1 ▸ MNAT1 ▸ MOCOS ▸ GAL ▸
BCL3 ▸ PRL ▸ ADM ▸ PTK6 ▸ SOCS1 ▸ FGB ▸ MAP3K14 ▸
IFNA10 ▸ CCR1 ▸ IFNA21 ▸ CCR4 ▸ ECM1 ▸ IFNA16 ▸ TGFB2 ▸
IFNA1 ▸ IFNA7 ▸ CXCR1 ▸ GCHFR ▸ CCR10 ▸ PRG2 ▸ MAP2K1 ▸
SETBP1 ▸ CD276 ▸ PRG3 ▸ STAT5A ▸ IFNA6 ▸ RETN ▸ IFNA13 ▸
RELB ▸ ADAM17 ▸ SLC22A3 ▸ APP ▸ JAK1 ▸ IKBKAP ▸ CD8A ▸
CEBPD ▸ MOK ▸ SPHK1 ▸ PRG4 ▸ IL2RB ▸ ACE ▸ LDLR ▸
ETS2 ▸ NEDD9 ▸ MSH3 ▸ CD44 ▸ ECM2 ▸ CCR8 ▸ IFNA5 ▸
CRAT ▸ TP53 ▸ CSE ▸ IFNA8 ▸ NOTCH1 ▸ IFNA17 ▸ LIPA ▸
PHKA2 ▸ ACP2 ▸ IFNA14 ▸ CCR9 ▸ NLRP3 ▸ CEL ▸ CADM1 ▸
TNFRSF1A ▸ MSH2 ▸ MSH4 ▸ PLAUR ▸ PAM ▸ TRAM1 ▸ OCLN ▸
ABCA1 ▸ F2RL1 ▸ CD55 ▸ GHR ▸ SERPING1 ▸ TNFRSF1B ▸ HDAC11 ▸
TGFB3 ▸ SLCO6A1 ▸ TNP2 ▸ F2R ▸ BCL5 ▸ UCP2 ▸ APCS ▸
NOTCH4 ▸ TXN ▸ SYK ▸ ATF3 ▸ CRYGEP ▸ IGFBP3 ▸ EIF4EBP1 ▸
TRAM2 ▸ MAF ▸ BCL9 ▸ WAS ▸ C9orf3 ▸ PLIN2 ▸ NOTCH2 ▸
CXCR2 ▸ HDAC3 ▸ TF ▸ BCL6 ▸ CCL24 ▸ MSH5 ▸ EDN3 ▸
EDN2 ▸ NOD1 ▸ PCBD1 ▸ OLR1 ▸ ANXA1 ▸ CNR2 ▸ NOTCH3 ▸
THBD ▸ PTPN11 ▸ ABCB1 ▸ TYK2 ▸ MSH6 ▸ NEU1 ▸ ALG1 ▸
SAA2 ▸ CAV3 ▸ SIGLEC7 ▸ RAC2 ▸ LTA ▸ SAA4 ▸ S100A8 ▸
FBXO32 ▸ CAMP ▸ GIF ▸ TNP1 ▸ SH3D19 ▸ JAK3 ▸ GPX5 ▸
SMC3 ▸ PPARGC1A ▸ SIGIRR ▸ BIRC3 ▸ NEU2 ▸ LPO ▸ POU2F2 ▸
COA4 ▸ PRKAG1 ▸ UPK3B ▸ MT4 ▸ FGFR3 ▸ SMC6 ▸ FXR2 ▸
DDX58 ▸ NEU3 ▸ ITGAX ▸ IFIT2 ▸ OXTR ▸ CX3CL1 ▸ PGC ▸
DDIT3 ▸ MRXS5 ▸ ICOSLG ▸ TYR ▸ NEU4 ▸ VIPR1 ▸ POMC ▸
RPTOR ▸ SCARB1 ▸ GPX4 ▸ NAALADL1 ▸ HMGCR ▸ HP ▸ A2M ▸
PRKAB2 ▸ MAP3K7 ▸ PGP ▸ SEC14L2 ▸ UBL3 ▸ SMC2 ▸ LOX ▸
GPX3 ▸ COA5 ▸ CAV2 ▸ SLC2A1 ▸ CD19 ▸ GPX6 ▸ ISG15 ▸
ADCY9 ▸ CTSB ▸ SMC5 ▸ FADD ▸ GPX7 ▸ S12 ▸ PRDX1 ▸
CTRL ▸ JUNB ▸ AGXT ▸ PTX4 ▸ PLTP ▸ TECR ▸ CDC42 ▸
CEBPZ ▸ GATA2 ▸ EPB42 ▸ WNT2 ▸ MARCKS ▸ GATA3 ▸ GPX8 ▸
S7 ▸ GFAP ▸ GIT1 ▸ CYBB ▸ CD38 ▸ MTA2 ▸ GAST ▸
CDH13 ▸ NPPA ▸ CNP ▸ FXR1 ▸ CES1 ▸ GPX2 ▸ CTLA4 ▸
PRKAG2 ▸ ELAVL1 ▸ COA1 ▸ TOLLIP ▸ CYP2B6 ▸ PRKAA2 ▸ STX1A ▸
ACO1 ▸ PRKAA1 ▸ PRKAB1 ▸ SLC7A2 ▸ COA6 ▸ GPX1 ▸ ACHE ▸
SMC4 ▸ CD8B ▸ PLCG1 ▸ ARC ▸ CETP ▸ JUND ▸ TSPO ▸
FPR1 ▸ CD28 ▸ CCL18 ▸ TRAF1 ▸ S11 ▸ VIP ▸ CD1A ▸
CCND2 ▸ COA3 ▸ CHD4 ▸ PLAT ▸ CIITA ▸ ALPI ▸ ANXA5 ▸
NPY4R ▸ HDAC6 ▸ MET ▸ EIF4E ▸ GSK3B ▸ AQP5 ▸ TFRC ▸
LGALS3 ▸ IGH ▸ CYP1A2 ▸ IDS ▸ MLST8 ▸ CAPN15 ▸ SDC4 ▸
GALT ▸ ETS1 ▸ HPGDS ▸ PARP3 ▸ PRKAR2B ▸ EPS15 ▸ MEPE ▸
CLDN1 ▸ SMN1 ▸ BCAP31 ▸ CAPN14 ▸ SLC9A1 ▸ CAPN6 ▸ EPS8 ▸
TPGS2 ▸ CAPN9 ▸ ACAN ▸ LRP1 ▸ ESAM ▸ KLF4 ▸ PPARD ▸
PRKAR1A ▸ ADAMTS5 ▸ CLU ▸ FCGR1A ▸ RPS6KB1 ▸ RHO ▸ MCM7 ▸
ADCY3 ▸ PGR ▸ TRIM63 ▸ PTHLH ▸ KHSRP ▸ CTSL ▸ SMAD4 ▸
MAP2K2 ▸ ABL1 ▸ PARP6 ▸ CD5 ▸ CORO2A ▸ NQO1 ▸ MCM4 ▸
PDCD1LG2 ▸ PLA2G7 ▸ INSR ▸ TNFSF13 ▸ GSR ▸ CAPN1 ▸ EPB41 ▸
GPS2 ▸ PRDX5 ▸ HDAC4 ▸ ERP27 ▸ CCL4L2 ▸ ADCY4 ▸ MST1R ▸
FMR1 ▸ FGF9 ▸ IRG1 ▸ IL1RAP ▸ ERP44 ▸ LAMP5 ▸ BCR ▸
MT-CYB ▸ CYP4F8 ▸ TBL1X ▸ APOA1 ▸ ERF ▸ NPR1 ▸ REG3A ▸
CAPN13 ▸ C1QA ▸ PRKAR1B ▸ MICE ▸ PARP9 ▸ GATA6 ▸ NFKBIZ ▸
SST ▸ ADCY1 ▸ STAR ▸ RSAD2 ▸ AQP8 ▸ HSP90AA1 ▸ CYP4F2 ▸
FEV ▸ PKD1 ▸ S100A9 ▸ CD1D ▸ TPGS1 ▸ TPX2 ▸ PLN ▸
HAMP ▸ AQP1 ▸ PPP2R1A ▸ QRICH1 ▸ SREBF1 ▸ TPO ▸ SPAG8 ▸
IFN1@ ▸ CNR1 ▸ LAMP1 ▸ C5AR1 ▸ PARP2 ▸ FOXP3 ▸ AQP4 ▸
KITLG ▸ TFAP2A ▸ FPR2 ▸ MCM5 ▸ PRX ▸ CAPN12 ▸ DOK3 ▸
CPP ▸ CADM2 ▸ EDNRA ▸ KLK3 ▸ LAMP2 ▸ HDAC9 ▸ HDAC7 ▸
NCOR1 ▸ PMPCB ▸ PDCD2 ▸ PARP15 ▸ CYP4F12 ▸ IL6R ▸ SERPINB6 ▸
IKBKE ▸ PRKACB ▸ IL2RG ▸ G6PD ▸ MARCO ▸ ADCY7 ▸ CCL1 ▸
PVR ▸ HDAC5 ▸ CAPN5 ▸ S1PR3 ▸ IL13RA1 ▸ HDAC10 ▸ MAP2K6 ▸
MTDH ▸ PRKACG ▸ IL1R2 ▸ TAT ▸ TBL1XR1 ▸ OSM ▸ MUC5B ▸
ERP29 ▸ ADCY8 ▸ CADM4 ▸ SLC11A2 ▸ CADM3 ▸ PPP2CA ▸ PRKCB ▸
PDGFA ▸ NTRK1 ▸ SIRT1 ▸ WNT5A ▸ CTNNB1 ▸ PARP8 ▸ PRDM1 ▸
GLA ▸ TUBGCP2 ▸ CROT ▸ AMBP ▸ BDKRB1 ▸ PARP10 ▸ AGT ▸
USP7 ▸ ADCY2 ▸ MCM6 ▸ PLCG2 ▸ ADCY10 ▸ P2RX4 ▸ NTF3 ▸
PPP2R2B ▸ MAP2K3 ▸ RHOB ▸ ITGB1 ▸ NR1I2 ▸ RASIP1 ▸ CPZ ▸
NANOS1 ▸ MTA1 ▸ MAL ▸ NR4A1 ▸ RNPEP ▸ HCLS1 ▸ USP14 ▸
GATA5 ▸ NCF4 ▸ MCS ▸ GATA1 ▸ IL18BP ▸ ITGAL ▸ CAPN10 ▸
CES3 ▸ NDUFAB1 ▸ CX3CR1 ▸ VDR ▸ SLC5A1 ▸ PECAM1 ▸ MCM2 ▸
PIR ▸ CAPN2 ▸ CAPN3 ▸ AQP2 ▸ SPHK2 ▸ F12 ▸ PARP16 ▸
ASS1 ▸ MCOLN1 ▸ HDAC8 ▸ C1QB ▸ PARP4 ▸ CAPN11 ▸ PKD2 ▸
RIPK2 ▸ C4BPA ▸ LGALS1 ▸ SP100 ▸ CYP4F11 ▸ PLEK ▸ ADCY5 ▸
MBD3 ▸ VWF ▸ CYP4F3 ▸ NPY ▸ LTC4S ▸ AKT1S1 ▸ TIMP3 ▸
PKD3 ▸ PARP14 ▸ TXNRD2 ▸ KCNH4 ▸ CYP4F22 ▸ PARP12 ▸ MCM3 ▸
S1PR1 ▸ PDGFB ▸ FOSL1 ▸ FGF21 ▸ CAPN8 ▸ ELANE ▸ CD58 ▸
ISG20 ▸ CES2 ▸ GATA4 ▸ FGF2 ▸ PARP11 ▸ PTEN ▸ FST ▸
CYP1A1 ▸ PRKAR2A ▸ QRICH2 ▸ SDC2 ▸ ADCY6 ▸ PRTN3 ▸ DST ▸
KCNMA1 ▸ SMAD7 ▸ CD9 ▸ LAMP3 ▸ CAPN7 ▸ ACSL1 ▸ NR3C1 ▸
COPS4 ▸ PCAF ▸ ARHGAP29 ▸ CREBBP ▸ TAF1 ▸ COPS2 ▸ SMARCD1 ▸
ONECUT1 ▸ GPS1 ▸ GTF3A ▸ TLX2 ▸ RFX3 ▸ MID1 ▸ BNC2 ▸
COPS6 ▸ UBC ▸ CDK4 ▸ GTF2A1 ▸ GTF2E1 ▸ COPS5 ▸ ZBTB3 ▸
Data information
Please see the Gene Interactions Track Manual.