◀ Back to IL5
IL5 — SEA
Text-mined interactions from Literome
Farah et al., Scand J Immunol 2000
(Granuloma...) :
Group B animals had low
SEA induced IFN-gamma levels and elevated
IL-5 levels, although these were lower than group C. SEA induced IL-10 was low in both groups A and B as compared to group C ( P < 0.01 )
King et al., Parasite Immunol 2001
(Schistosomiasis mansoni) :
By contrast, CD4+ splenocytes produced comparatively little cytokine release by endogenous antigen, whereas exogenous
SEA strongly
induced IL-4,
IL-5 , IL-10 and IFN-gamma production and lymphocyte proliferation that correlated poorly with the dynamics of granulomatous inflammation
Shen et al., Parasite Immunol 2003
(Schistosomiasis japonica) :
S. japonicum soluble worm antigen ( SWAP ) and
soluble egg antigen (SEA) stimulated IL-4,
IL-5 and IFN-gamma production in whole-blood cultures were measured by ELISA
Ghadimi et al., Immunobiology 2008
(Hypersensitivity) :
Lactobacilli and bifidobacteria reduced
SEA stimulated IL-4 and
IL-5 production more effectively in PBMCs from healthy subjects than from allergic patients
Tweyongyere et al., BMC infectious diseases 2011
(Pregnancy Complications, Parasitic...) :
There was some evidence that maternal infection intensity was positively associated with cord blood IL-5 and IL-13 responses to SWA, and
IL-5 responses to
SEA , and that this association was modified by treatment with praziquantel
Oliveira et al., Am J Trop Med Hyg 2012
(Disease Susceptibility...) :
Mononuclear cells of resistant subjects produced higher levels of
interleukin-5 (IL-5) , IL-13 and interferon-? upon
stimulation with
soluble egg antigen (SEA) compared with infected persons
Ferreira et al., Mem Inst Oswaldo Cruz 2012
(Chronic Disease...) :
We demonstrate that stimulation with
SEA induced prominent lymphocyte proliferation and high levels of tumour necrosis factor (TNF)-a,
interleukin (IL)-4 and IL-10 secretion in both OST and non infected individuals ( NI )
De Souza et al., Journal of parasitology research 2012
:
The levels of
IL-5 in
response to
SEA were higher in individuals with moderate to severe fibrosis ( 310.9?pg/mL ) compared to individuals without fibrosis ( 36.8?pg/mL ; P = 0.0418 )
König et al., Int Arch Allergy Immunol 1995
(Dermatitis, Atopic) :
In contrast to normal donors T cells from donors with AD predominantly express mRNA for IL-4,
IL-5 , and only diminished levels for IFN-gamma and IL-12 upon
stimulation with SEB and
SEA
Hobeika et al., Biochem Biophys Res Commun 1996
:
A synthetic peptide of this region, SEA ( 121-149 ), blocks
SEA binding to class II MHC molecules and
induces interleukin-1 and tumor necrosis factor production in monocytes