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STAT3 → RhoA: " We also found that although active RhoA , Rac1, and Cdc42 could all mediate Ser-727 and Tyr-705 phosphorylation and nuclear translocation of STAT3 , the Rho GTPases were able to induce STAT3 activation independently of the interleukin-6 autocrine pathway, and active RhoA, Rac1, or Cdc42 could not form a stable complex with STAT3 as previously suggested, indicating an unappreciated mechanism of STAT3 activation by the Rho GTPases "
STAT3 → Rac1: " We also found that although active RhoA, Rac1 , and Cdc42 could all mediate Ser-727 and Tyr-705 phosphorylation and nuclear translocation of STAT3 , the Rho GTPases were able to induce STAT3 activation independently of the interleukin-6 autocrine pathway, and active RhoA, Rac1, or Cdc42 could not form a stable complex with STAT3 as previously suggested, indicating an unappreciated mechanism of STAT3 activation by the Rho GTPases "
Tyr-705 → Cdc42: " We also found that although active RhoA, Rac1, and Cdc42 could all mediate Ser-727 and Tyr-705 phosphorylation and nuclear translocation of STAT3, the Rho GTPases were able to induce STAT3 activation independently of the interleukin-6 autocrine pathway, and active RhoA, Rac1, or Cdc42 could not form a stable complex with STAT3 as previously suggested, indicating an unappreciated mechanism of STAT3 activation by the Rho GTPases "
Tyr-705 → RhoA: " We also found that although active RhoA , Rac1, and Cdc42 could all mediate Ser-727 and Tyr-705 phosphorylation and nuclear translocation of STAT3, the Rho GTPases were able to induce STAT3 activation independently of the interleukin-6 autocrine pathway, and active RhoA, Rac1, or Cdc42 could not form a stable complex with STAT3 as previously suggested, indicating an unappreciated mechanism of STAT3 activation by the Rho GTPases "
Tyr-705 → Rac1: " We also found that although active RhoA, Rac1 , and Cdc42 could all mediate Ser-727 and Tyr-705 phosphorylation and nuclear translocation of STAT3, the Rho GTPases were able to induce STAT3 activation independently of the interleukin-6 autocrine pathway, and active RhoA, Rac1, or Cdc42 could not form a stable complex with STAT3 as previously suggested, indicating an unappreciated mechanism of STAT3 activation by the Rho GTPases "
STAT3 → RhoA: " The RhoA induced STAT3 activation partly depended on Rho associated kinase (ROK) and involved multiple effector signals as revealed by the examination of effector domain mutants of RhoA "
cyclin D1 → STAT3: " STAT3 was required for the RhoA induced NF-kappaB and cyclin D1 transcription and was involved in NF-kappaB nuclear translocation "
cyclin D1 → RhoA: " STAT3 was required for the RhoA induced NF-kappaB and cyclin D1 transcription and was involved in NF-kappaB nuclear translocation "
NF-kappaB → STAT3: " STAT3 was required for the RhoA induced NF-kappaB and cyclin D1 transcription and was involved in NF-kappaB nuclear translocation "
NF-kappaB → RhoA: " STAT3 was required for the RhoA induced NF-kappaB and cyclin D1 transcription and was involved in NF-kappaB nuclear translocation "
RhoA → STAT3: " Furthermore, loss of STAT3 expression inhibited RhoA promoted cell proliferation and blocked RhoA or ROK induced anchorage independent growth "