Gene interactions and pathways from curated databases and text-mining

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EPHB2 — ME2

Text-mined interactions from Literome

Ren et al., PloS one 2010 (Leukemia, Erythroblastic, Acute) : We found that silencing of ME2 leads to phospho-ERK1/2 inhibition, phospho-AKT activation, increased GATA-1 expression and diminished vimentin expression
Koganti et al., Gend Med 2012 : Pretreatment of cells with the MEK inhibitor PD98059 prevented 2ME2 induced ERK1/2 phosphorylation and down-regulation of AT1R expression, which suggests that the observed inhibitory effect is mediated through ERK1/2 signaling intermediates