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DGKA — NFKB1

Text-mined interactions from Literome

Yanagisawa et al., Biochim Biophys Acta 2007 (Melanoma) : Conversely, DGKalpha-knockdown considerably inhibited the NF-kappaB activity
Kai et al., FEBS Lett 2009 : We recently reported that diacylglycerol kinase (DGK) alpha enhanced tumor necrosis factor-alpha (TNF-alpha) induced activation of nuclear factor-kappaB (NF-kappaB) ... Moreover, knockdown and overexpression of PKCzeta suppressed and synergistically enhanced DGKalpha mediated NF-kappaB activation, respectively ... These results strongly suggest that DGKalpha positively regulates TNF-alpha dependent NF-kappaB activation via the PKCzeta mediated Ser311 phosphorylation of p65/RelA