Gene interactions and pathways from curated databases and text-mining

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EPC2 — VEGFA

Text-mined interactions from Literome

Iwaguro et al., Circulation 2002 (Disease Models, Animal...) : In vitro, ex vivo murine vascular endothelial growth factor ( VEGF ) 164 gene transfer augmented EPC proliferative activity and enhanced adhesion and incorporation of EPCs into quiescent as well as activated endothelial cell monolayers
Li et al., FASEB J 2006 (Neovascularization, Pathologic) : Our data suggest local VEGF and/or PlGF expression promote vasculogenesis ; VEGF plays a role in EPC recruitment and subsequent formation of functional vessels
Bleiziffer et al., J Cell Mol Med 2009 : Taken together, T17b EPC secrete increased levels of VEGF when submitted to either hypoxia or differentiation and can be differentiated into mature endothelial cells not only in cell and matrigel cultures but also in a fibrin matrix that is FDA approved for clinical application
Kinoshita et al., Clinical ophthalmology (Auckland, N.Z.) 2011 : PPV + PPL + EPC + SO tamponade might have prevented acute increases of vascular endothelial growth factor and inflammatory cytokine production postoperatively and resulted in good vision in patients with NVG
Chen et al., Clin Exp Nephrol 2013 (Kidney Failure, Chronic...) : A link between CKD and increased mononuclear cell apoptosis ( MCA ) in circulation has been reported but the effect of vascular endothelial growth factor ( VEGF ) and stromal cell derived factor (SDF)-1a, two angiogenesis factors, on circulating EPC levels in CKD has not been clarified
Kanzler et al., Basic Res Cardiol 2013 : We have identified a role for EPC derived proangiogenic MIF, VEGF and MIF receptors in EPC recruitment following hypoxia, EPC differentiation and subsequent tube and vessel formation, whereas CXCL12, a mediator of early EPC recruitment, does not contribute to the remodeling process