Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
TRAF2
→
E2F1
(decreases)
Evidence: Activation of TNF receptors in response to TNF-a results in the stimulation of NF-kB via TNF receptor-associated factor 2 (TRAF2), which contributes to inhibition of cell death [58]. Importantly, E2F1 expression sensitizes cells to apoptosis by downregulation of TRAF2 protein levels, thereby inhibiting anti-apoptotic NF-kB signaling
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *