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STAT1 — TGFB1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Park et al., J Immunol 2005
:
Consistent with a direct role for Shp-1,
TGF-beta1 's
inhibition of IFN-gamma induced
Stat1 phosphorylation was sensitive to the general PTP inhibitor pervanadate
Takaki et al., Genes Cells 2006
:
We also found that
TGF-beta1 directly
inhibited IFN-gamma induced
STAT1 activation by reducing STAT1 tyrosine phosphorylation ... Reduced
activation of
STAT1 by
TGF-beta1 was abrogated by the mutation in the IFNGR1 in which the serine residues of potential sites of phosphorylation by TGF-betaRI were replaced by alanine residues