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LIN28B — MYC

Text-mined interactions from Literome

Chang et al., Proc Natl Acad Sci U S A 2009 : We now show that Myc induces Lin-28B expression in multiple human and mouse tumor models
McCarty et al., Med Hypotheses 2012 (Neoplasm Metastasis...) : The transcription of Lin28B is promoted by NF-kappaB and by Myc ; hence, practical measures which antagonize NF-kappaB or Myc activity may complement the utility of metformin for boosting let-7 expression and controlling cancer stemness ; salsalate, antioxidants, tyrosine kinase and cox-2 inhibitors, ribavirin, vitamin D, gamma-secretase inhibitors ( when available ), and parenteral curcumin may have some utility in this regard