◀ Back to MYC

MYC — ZFP36

Text-mined interactions from Literome

Marderosian et al., Oncogene 2006 : Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt dependent manner via p38 MAPK signaling
Sohn et al., Gastroenterology 2010 (Carcinoma, Hepatocellular...) : In this study, we sought to determine whether deregulated expression of tristetrapolin (TTP) , a negative posttranscriptional regulator of c-Myc , confers resistance to the antiproliferative effects of TGF-beta1 on liver cancer cells
Rounbehler et al., Cell 2012 (Cell Transformation, Neoplastic...) : Notably, Myc directly suppresses transcription of Tristetraprolin ( TTP/ZFP36 ), an mRNA destabilizing AUBP, and this circuit is also operational during B lymphopoiesis and IL7 signaling