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IL8 — SPP2
Text-mined interactions from Literome
Mechtcheriakova et al., Cell Signal 2007
(Inflammation...) :
Silencing of
SPP2 expression in endothelial cells, in turn,
led to a marked reduction of TNF-alpha induced IL-1beta mRNA and protein and to a partial reduction of induced
IL-8 , suggesting a pro-inflammatory role of SPP2
Schleh et al., Respir Res 2010
:
SP-D increased the fraction of bronchial epithelial cells that bound SPP but not the fraction of cells that internalized SPP.
SPP induced secretion of
IL-8 was further increased by SP-D