Gene interactions and pathways from curated databases and text-mining

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IL8 — SPP2

Text-mined interactions from Literome

Mechtcheriakova et al., Cell Signal 2007 (Inflammation...) : Silencing of SPP2 expression in endothelial cells, in turn, led to a marked reduction of TNF-alpha induced IL-1beta mRNA and protein and to a partial reduction of induced IL-8 , suggesting a pro-inflammatory role of SPP2
Schleh et al., Respir Res 2010 : SP-D increased the fraction of bronchial epithelial cells that bound SPP but not the fraction of cells that internalized SPP. SPP induced secretion of IL-8 was further increased by SP-D